Musician Battles Stage Iv Colon Cancer

Wade Hayes performs at the Stars Go Blue For Colon Cancer benefit on March 6, 2012.

It could make a substantial difference in the number of lives saved.” Hayes had no family history of gastrointestinal disease, which is one of the reasons he ignored his symptoms for so long. In fact, when he walked into the hospital in November, he was in better shape than everyone in the waiting room, Robertson remembers. Since then, Hayes has lost 50 pounds and is struggling to regain a sense of normalcy through multiple rounds of chemotherapy. He’s fighting an uphill battle — a 2004 study published in the Journal of the National Cancer Institute estimated the five-year survival rate for stage IV colon cancer to be 8.1%, and an institute study of cancer data put the survival rate at 6%. “It hurts like hell,” Hayes says of his recovery. “I always thought of myself as a man’s man, but I just discovered what a wuss I am.” Wade Hayes performs at the Stars Go Blue For Colon Cancer benefit on March 6, 2012. Thankfully, Hayes is anything but alone in Nashville. Willie Nelson called from Hawaii to wish him well. Kix Brooks helped him connect with the best doctors in the city. Jay DeMarcus from Rascal Flatts arranged for a private room at Vanderbilt hospital. “That part of it has been really shocking for me. I had no idea how many people cared about me or even knew I existed.” Robertson says that’s the kind of person Hayes is — modest to a fault; an introvert who enjoys reading detective dramas and has no desire to just sit around.

learn more here http://www.cnn.com/2012/03/22/health/wade-hayes-colon-cancer/index.html

Colon Cancer Screenings Work, Twin Studies Report

Colonoscopy, sigmoidoscopy and even fecal blood

29 issue of the New England Journal of Medicine. Two other recommended screening methods, however, also greatly reduce colon cancer mortality, the researchers found. Flexible sigmoidoscopy provides a 40 percent lower risk of dying from colon cancer, while annual fecal blood testing offers a 32 percent reduced death risk. “The inclusion of all these tests in the guidelines of major organizations continues to make sense,” said Dr. Durado Brooks, director of prostate and colorectal cancers for the American Cancer Society. “Quite honestly, many patients don’t have access to colonoscopy or are not willing to undergo a screening colonoscopy. Many studies have shown that offering patients options will increase the likelihood that they will complete some form of screening, and that is what is most important.” The results come from a pair of studies testing the long-term health benefits of screening for colon cancer. The first study investigated the use of colonoscopy and flexible sigmoidoscopy among a group of almost 89,000 health professionals during a 20-year period. Colonoscopy uses a thin tube equipped with a camera to examine the entire length of the colon in a procedure for which patients are usually sedated. Flexible sigmoidoscopy is a similar procedure but with a shorter tube that examines less of the colon, so patients do not have to be sedated. The study found colonoscopy was more effective in preventing cancer throughout the entire colon, but that both procedures greatly reduced the overall risk of colon cancer death, said Dr. Andrew Chan, an assistant professor at the Massachusetts General Hospital Gastrointestinal Unit and the co-senior author of the report. “Colonoscopy was superior to flexible sigmoidoscopy in terms of reducing the risk of colon cancer throughout the colon,” Chan said. “But this study really does support the existing guidelines and recommendations for individuals to undergo screening with either colonoscopy or sigmoidoscopy. I think this study shows there’s a very real impact on the risk of developing cancer and dying of cancer.” The second study focused on the fecal occult blood test, which uses chemical agents to detect trace amounts of blood in a person’s stool. Researchers led by Dr.

learn more http://www.webmd.com/colorectal-cancer/news/20130918/colon-cancer-screenings-work-twin-studies-report

Colon Cancer Stool Symptoms

Photo Credit toilet paper image by Aleksandr Ugorenkov from Fotolia.com Over 100,000 people were affected by colon cancer in 2010, according to estimates provided by the National Cancer Institute. This form of cancer affects the colon, the longest region of the large intestine. Colon cancer often results in stool changes in people with this disease. People who develop any of the stool symptoms associated with colon cancer should seek care from a physician as soon as possible. Loose or Hard Stools Abnormal cancer cell growth within the colon can disrupt the way in which fluids are absorbed and released within the digestive tract. When the colon does not absorb enough water, people with colon cancer can produce frequently loose, runny stools, a symptom referred to as diarrhea, the NCI explains. Alternatively, excessive absorption of fluids from the digestive tract can make it difficult for a person to have a normal bowel movement, a symptom called constipation. People with constipation may excrete small, hard masses of stool that are difficult or painful to produce. Chronic bowel movement changes can be signs of alternate medical problems and should be reported to a doctor as soon as possible. You Might Also Like Complications of Colon Cancer Thin Stools Colon cancer can cause cancerous tumor growth within the large intestine. These growths narrow the digestive pathway, making it harder for ingested food products to pass through the body. Consequently, people with colon cancer can notice that their stools appear abnormally thin, the American Cancer Society reports. The production of narrow stools may also occur in conjunction with abdominal pain, cramping or gas. Bloody Stools Cancer cells can irritate the sensitive lining of the intestinal tract, causing red blood cells to enter the contents of the bowel. Blood within the colon can cause patients with colon cancer to produce bloody stools. The stools can appear abnormally red or dark, or a person may notice blood on the piece of toilet paper used to wipe the rectum after a bowel movement.

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Colon cancer screening tied to better outcomes

“It’s in line with its current use. It shows that colonoscopy appears to be beneficial in reducing deaths in those diagnosed with colorectal cancer,” said Dr. Chyke Doubeni, who studies colonoscopy use but wasn’t involved in the new research. Colon cancer is the third most common cancer and the second leading cause of cancer death in the U.S., according to the government-backed U.S. Preventive Services Task Force (USPSTF), which recommends that people between ages 50 and 75 get screened by colonoscopy every ten years. During a colonoscopy, a doctor uses a long flexible tube equipped with a tiny video camera to see the interior of the colon. According to the study authors, the incidence of colon cancer in the U.S. has dropped by about 6 percent since the first national colonoscopy guidelines were introduced in 2000 – mostly due to doctors catching and removing precancerous polyps during screening. Still, the U.S. Centers for Disease Control and Prevention reports that about 22 million people are not up-to-date with their colon cancer screenings. For the new study, Dr. Ramzi Amri and colleagues from Massachusetts General Hospital and Harvard Medical School in Boston analyzed data on all people who underwent colon cancer surgery at their hospital from 2004 through 2011. Their goal was to see whether those diagnosed with colon tumors after colonoscopy screenings had better outcomes than patients diagnosed after going to their doctors because they were experiencing symptoms, such as bleeding from the rectum. Amri and his colleagues had data on 217 people diagnosed after screening and 854 who were diagnosed based on symptoms or other tests. They found that in addition to being more likely to die, patients diagnosed with colon cancer based on symptoms were far more likely to have advanced disease, to have cancer that spread to other parts of their bodies and to have cancer that recurred.

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Patient Comments: Colon Cancer – Symptoms

Symptom Checker: Your Guide to Symptoms & Signs: Pinpoint Your Pain

We went to the doctor for about a year. They kept telling us it was ulcers, indigestion , etc. Finally they did CT scans and a colonoscopy and found a massive tumor . It was attaching to his liver and pelvic bone. They did surgery and thankfully he has been in remission for 7 years. Was this comment helpful? About a week later I had diarrhea again. My first thought was the stomach flu came back. After about 2 weeks of diarrhea bright red blood started to occur. I went to the doctor and she submitted me the same day for a CT scan followed by a colonoscopy a couple of days later. CT scan showed a shadow on my liver and colonoscopy revealed a malignant growth in my rectum a cancerous polyp in the colon. Followed by another CT scan and eventually a PET scan the diagnosis was stage 4 metastatic colon cancer that has spread to the liver. 2nd opinion at City of Hope came to the same conclusion. I was told it had spread only to the liver.

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Final Stage Colon Cancer Symptoms

For example, people who consumed an extra 90 grams of whole grains a day also had a 20 percent lower risk of colorectal cancer, according to the British Medical Journal review. However, that same study didn’t show a link between eating fiber from fruits and vegetables and a lowered colorectal cancer risk, meaning there may be something else in whole grains at work, too. Take Aspirin Researchers from the Leiden University Medical Center in the Netherlands found that people who take aspirin once a day have a 30 percent decreased risk of dying from colorectal cancer, if taken for at least a nine-month period. And, the benefit extended to after a person had been diagnosed with colorectal cancer. The researchers found that people who had already been diagnosed and who took aspirin had a 23 percent decreased risk of dying from the disease, compared with people who didn’t take it at all. Eat Chocolate (Maybe) The Daily Mail reported on a study in mice, published in the journal Molecular Nutrition and Food Research, showing that rats exposed to a carcinogen developed fewer colon cancer lesions than rats if they consumed high-cocoa diets. “Being exposed to different poisons in the diet like toxins, mutagens and procarcinogens, the intestinal mucus is very susceptible to pathologies,” study researcher Maria Angeles Martin Arribas, a researcher at the Institute of Food Science and Technology and Nutrition, said in a statement. “Foods like cocoa, which is rich in polyphenols, seems to play an important role in protecting against disease.” However, it’s important to note that this effect was tested only on mice. Consume Ginger Root Research published in the journal Cancer Prevention Research showed that taking 2 grams of ginger root supplement every day might have colon cancer-preventing powers. The researchers from the University of Michigan Medical School found that taking ginger root supplements helped to minimize signs of inflammation of the colon, which has been connected to colon cancer. Go To A Classical Music-Loving Doctor A study from the University of Texas Health Science Center showed that doctors who conduct colonoscopies while listening to Mozart are more likely to find polyps, which can lead to colon cancer, ABC News reported. The study showed that polyp-detection increased to 36.7 percent from 27.16 percent when the doctors listened to Mozart. Exercise Regularly A study in the journal Cancer Causes & Control showed that people who exercise or play sports five or more times a week can lower their risk of developing colorectal cancer, compared with those who don’t exercise regularly (or at all), Johns Hopkins University reported.

Why exercise might reduce colon cancer risk isn’t well understood. It may be because exercise enhances the immune system or because it reduces levels of insulin and insulin-like growth factors, all of which have been associated with colon cancer risk.

Eat Your Veggies A number of studies have linked the consumption of cruciferous vegetables with a decreased risk of colorectal cancer, Oregon State University reported, though the effect may depend on a person’s genetic risk. In particular, a study published in 2000 in the American Journal of Epidemiology, showed that people who ate the most cruciferous veggies in a day (about 58 grams per day, on average) had a lower risk of colon cancer compared with people who ate the fewest cruciferous veggies in a day (about 11 grams per day, on average), Oregon State University reported.

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Bowel Cancer Diagnosis Delayed As Patients Fail To Recognise Symptoms And Feel Embarrassment

There are roughly 100,000 new cases of colon cancer in the United States every year, according to the American Cancer Society. Roughly 45,000 patients will die of colon cancer every year. Patients with final stage colon cancer (also known as stage IV colon cancer) have the lowest survival rate among colon cancer patients. Pain Patients with final stage colon cancer may experience pain in the bone, as the cancer has spread to the bone. Patients may experience pain in the back or in the rib. Pain tends to be localized and continuous. In some cases, patients may suffer from bone fracture due to metastatic colon cancer in the bone. If the cancer has spread to the brain, patients may experience severe headache, blurred vision, dizziness, confusion and disorientation. Computed tomography (CT) or magnetic resonance imaging (MRI) can be used to scan the brain and to determine the extent of the tumor in the head. Jaundice (yellowing of skin), fever, loss of appetite, swelling of the leg or abdominal pain may indicate that the liver has been affected. You Might Also Like Types of Colon Cancer Weight Loss Patients with final stage colon cancer may experience losing weight of 10 percent or more, according to a 2004 review published in “Family Practice.” Weight loss is also an indication of metastatic cancer in the liver. Shortness of Breath Shortness of breath is an indication that the cancer has spread to the lung. Other indications of metastatic colon cancer in the lung include chest pain, cough and cough producing bloody sputum. Other Symptoms Patients may observe bubbles in the urine (pneumateria). This is the sign that the cancer affects the bladder. Patients with final stage colon cancer might also have symptoms that are common to colon cancer, such as rectal bleeding, constipation, fatigue, anemia, obstruction and diarrhea, according to a 2004 review published in “American Journal of Gastroenterology.” Roughly 50 to 70 percent of colon cancer patients experience rectal bleeding and changes in bowel habit.

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Heavy People More Likely To Have Colon Polyps

A man walks past the New York Stock Exchange after trading hours in New York August 17, 2009.REUTERS/Lucas Jackson

Although less than 10 percent become cancerous, most colon cancers are thought to develop from polyps. Previous studies have made the connection between obesity and colon cancer – a link recognized by the National Cancer Institute – but the new study is the first to point to a higher risk of adenomas in heavy people. By focusing on “precancerous” cell changes, researchers were hoping to shed more light on whether cancer screening recommendations should take a person’s weight into account. “Because there is a known association between obesity and cancer, there is a logical extension to expect a connection between obesity and the step before cancer, which is adenoma,” said Dr. Hutan Ashrafian from Imperial College, London, who co-authored the study. The findings can’t say whether obesity causes polyps by itself. But if it does, that could be bad news for a world where obesity is on the rise. According to the World Health Organization, about 500 million people worldwide are obese; colon cancer killed more than half a million people worldwide in 2008, the most recent figures from the WHO show. For the new research, Ashrafian and his colleagues analyzed data from 23 studies involving more than 100,000 people across the U.S., Asia and Europe, looking at the relationship between polyps and body mass index, or BMI, a measure of weight relative to height. All the studies followed World Health Organization guidelines that define people with a BMI over 25 as overweight and above 30 as obese. In most studies, polyps were identified during colonoscopy procedures in which a flexible tube tipped with a camera is guided though the rectum and into the colon. Self-reported questionnaires were used in two large studies. Overall, researchers found that 22 percent of overweight and obese people had colon polyps, compared to 19 percent in people of normal weight, and the polyp risk grew with increasing BMI.

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Health Check: Does Processed Meat Cause Bowel Cancer?

Provides funding as a Member of TheConversation. Where experts find jobs Processed meats and large quantities of cooked red meats (more than 500g a week) increase your risk of bowel cancer. Flickr/Pabo76 Each year around 14,400 Australians are diagnosed with bowel (colon and rectal) cancer. Its the second most common newly diagnosed cancer after lung cancer and claims around 3,980 lives a year. The good news is that bowel cancer has a high cure rate if detected early. And there is convincing evidence that you can reduce your risk of it by regularly eating foods that are high in dietary fibre, such as wholegrains, legumes, pulses, high fibre cereals, vegetables and fruit. In fact, for every ten grams of fibre you consume per day, your risk reduces by 10%. Being physically active for at least 30 minutes a day also decreases your risk of bowel cancer. But the other side of the risk equation is bad news for those who love a good deli meat: the regular consumption of processed meat increases your chances of getting bowel cancer. What does the evidence say? Red meat contains important nutrients such as protein, iron, zinc, vitamins B12, thiamin, riboflavin and niacin. But there is convincing evidence that eating more than 500 grams of cooked meat per week is risky. The latest World Cancer Research Fund meta-analysis of 12 separate studies indicates that for every 100 gram increase in red meat a day there is a 17% increase in bowel cancer risk. For processed meat, there appears to be no completely safe level of intake, with a meta-analysis of 13 studies finding an 18% increase in bowel cancer risk for every 50-gram increase in daily intake. How much do we eat?

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Key Link Responsible For Colon Cancer Initiation, Metastasis

“We have demonstrated that CXCR2 mediates a critical step in the setup of the blood circulatory machinery that feeds tumor tissue. This provides an important new clue for the development of therapeutic targets to neutralize the effect of CXCR2 on colon cancer.” The DuBois’ Laboratory for Inflammation and Cancer, which includes lead author Hiroshi Katoh, and colleagues Dingzhi Wang, Takiko Daikoku, Haiyan Sun, and Sudhansu K. Dey, published the results in the November 11 issue of Cancer Cell. The results provide critical new clues toward the prevention of colorectal cancer, the second leading cause of cancer deaths in the U.S. Despite the availability of colonoscopy screening, the 5-year survival rate remains low, due to a large number patients presenting with advanced stages of the disease. Currently, there are no clinically available blood tests for the early detection of sporadic colon cancer. Inflammation has long been associated with increasing one’s risk for colon cancer. For instance, more than 20 percent of patients with a form of inflammatory bowel disease (IBD) develop colorectal cancer within 30 years of diagnosis. This colitis-associated cancer has a slow progression, but a very poor response to treatment and a high mortality rate. Researchers have known that the broad mechanisms of cancer involve an interplay with the immune system response that includes: recruiting immune cells that influence the tumor microenvironment, escaping from host immunosurveillance and suppression, shifting of the host immune response, and tumor-associated angiogenesis to establish the blood supply. For the study, the research team first “knocked-out” or removed the CXCR2 gene in mice, and found that the signs typically associated with inflammation were prevented. Furthermore, they demonstrated that CXCR2 dramatically suppressed colonic inflammation and the colitis associated tumor formation, growth and progression in mice. CXCR2 decorates the outer part of immune cells called myeloid-derived suppressor cells, or MDSCs, that work to block the immune response of killer CD8+ T cells. In the knockout mice, without CXCR2 present, the MDSC cells could no longer migrate from the circulatory system to the colon, dodge the killer CD8+ T cell immune response, and feed the blood supply of the tumor environment.

consultant http://www.sciencedaily.com/releases/2013/11/131111122101.htm

Genomic Health Announces Colon Cancer Publication Supporting Wider Oncotype DX(R) Utilization

Two-thirds (67 percent) of changes in treatment recommendations were decreases in treatment intensity (changes from chemotherapy to observation or from oxaliplatin-containing chemotherapy to treatment with fluoropyrimidine monotherapy), while one-third (33 percent) of changes were increases in treatment intensity. “In the past, selection of stage II patients for chemotherapy treatment following surgery has been based on a limited set of clinical and pathologic markers that are uninformative for most patients,” said Thomas H. Cartwright, M.D., Florida Cancer Affiliates, Ocala, Florida, and the principal investigator of this study. “The Oncotype DX colon cancer test has been clinically validated to provide a quantitative, individualized Recurrence Score and has been very helpful in treatment planning. The test represents an important advancement in bringing personalized medicine into today’s clinical setting to benefit patients.” To read the publication titled “Effect of the 12-Gene Colon Cancer Assay Results on Adjuvant Treatment Recommendations in Patients with Stage II Colon Cancer,” visit: http://www.cmrojournal.com Separately, the Journal of Clinical Oncology accepted for publication positive results from the third successful validation of the Oncotype DX colon cancer test in patients with stage II disease and first validation study in patients with stage III disease. Presented at the 2012 European Society for Medical Oncology Congress, these findings demonstrate that incorporation of the Recurrence Score may better inform adjuvant therapy decisions for certain patients with stage III disease, as well as those with stage II colon cancer. About Genomic Health Genomic Health, Inc. (NASDAQ: GHDX) is the world’s leading provider of genomic-based diagnostic tests that address the overtreatment of early stage cancer, one of the greatest issues in healthcare today. The company is applying its world-class scientific and commercial expertise and infrastructure to lead the translation of massive amounts of genomic data into clinically-actionable results throughout the cancer patient’s journey, from screening and surveillance, to diagnosis, to treatment selection and monitoring. Genomic Health’s lead product, the Oncotype DX(R) breast cancer test, has been shown to predict the likelihood of chemotherapy benefit as well as recurrence in invasive breast cancer and has been shown to predict the likelihood of recurrence in ductal carcinoma in situ (DCIS). In addition to this widely adopted test, Genomic Health provides the Oncotype DX colon cancer test, the first multi-gene expression test developed for the assessment of risk of recurrence in patients with stage II and stage III disease, and the Oncotype DXprostate cancer test, which predicts disease aggressiveness in men with low risk disease. As of June 30, 2013, more than 19,000 physicians in over 70 countries had ordered more than 375,000 Oncotype DX tests. The company is based in Redwood City, California with European headquarters inGeneva, Switzerland.

helpful resources http://online.wsj.com/article/PR-CO-20131105-906989.html

Veterans Treatment Court In Santa Barbara Graduates First Class

treatment court

Even years after his return, Lopez could not resume life as he had before his tour of duty. “I still hadn’t come home,” he said. He didn’t realize he had PTSD until hearing former UCSB professor and Rep. Walter Capps speak about it during a UCSB course called “The Vietnam Experience.” “He was damaged there in the Gulf War,” Eskin said, and Lopez ended up in Eskin’s courtroom. Though Santa Barbara County has had a substance abuse treatment court since 1996, Lopez said being surrounded by other veterans “changes everything.” Lopez now lives in the Los Angeles-based Bimini Recovery House and hopes to give back to the community now that he’s completed his court program. Several from the court system spoke Friday, including Deputy District Attorney Michael Carrozzo, a former JAG officer who helped Eskin coordinate the program, and public defender Rai Montes de Oca. Santa Barbara County District Attorney Joyce Dudley said her aunt served as a psychiatric nurse during World War II , and Dudley carried the flag that had been presented to the family after her aunt’s death. She died with two unfulfilled hopes, Dudley said, the first being that gay service members would be openly accepted and that people would more fully understand that war came at a cost to mental and physical health. If her aunt could have seen the treatment court in operation in Santa Barbara County today, Dudley said, “she would be in awe.” First District county Supervisor Salud Carbajal , who is a veteran who served in the U.S. Marine Corps , also spoke. “While you may have fallen down a time or two, you again have risen to the occasion,” he told the graduates. Second District Supervisor Janet Wolf also spoke, and told the graduates that the community was there to support them. “This is one step in the journey,” she said. “It’s OK to ask for help and support.” Sen. Hannah-Beth Jackson said she has watched the program unfold as her husband has worked to move it forward. “Redemption is far better than retribution, and we understand that,” she said. Santa Barbara police officer Craig Burleigh works with veterans who have ended up homeless and live on the streets.

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New Spa Treatment Will Leave Your Skin Silky Smooth and Also Cover Your Body in Hungry Eels

There are the snails , whose mucus leaves a trail of anti-aging and skin-rejuvenating properties on the skin of spa goers. There are the skin-eating fish pedicures and the bee-venom facials and the python massages . Now eels may be invading a spa near you. The Guardian reports that some spas in China are offering an immersive full-body exfoliating experience where spa goers can climb into a bathtub filled with tiny eels, each about the size of a pencil. The eels will then proceed to eat the dead skin cells off the beauty seekers body. If you can stand the treatment, the result is supposedly smoother, softer skin. While spas in the U.S. havent started offering the eel baths yet, UK health inspectors have been tasked with keeping an eye out for the imported treatment. A spokesman from theChartered Institute for Environmental Health (CIEH), which represents health inspectors, told the UKs Daily Mail that it was vital that any new beauty treatment be subjected to a risk assessment to consider its impact on the public or the animals involved. The Guardian also quotes Wendy Nixon, a health and safety consultant, who told CIEH that there were problems with the procedure, especially for those wearing loose-fitting swimwear. Men in particular may want to avoid this particular exfoliating technique.

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