Cosmetic Treatment Can Open Door To Bacteria

The precise figures for Denmark are not known, but there can be no doubt that the numbers are rising rapidly — and a rise in the number of treatments will inevitably make the side effects more evident. “Because a lot of cosmetic practitioners refuse to accept that side effects from filler procedures are caused by bacteria, claiming that such problems are caused by allergic reactions, the usual procedure has been to treat with steroids. This is actually the worst possible treatment because steroid injections exacerbate the condition and give the bacteria free rein. Fortunately, many of the filler producers have now become aware of the risk of bacteria and recognise that the gel can act as a bacterial incubator,” says Associate Professor Thomas Bjarnsholt from the Department of International Health, Immunology and Microbiology. He continues: “The problem will become very serious when the treatment becomes so widespread that people are able to walk in off the street to have their wrinkles smoothed out. Experts recommend keeping facial skin free from make-up for a month before undergoing a treatment involving fillers. Good hygiene is always important. Even when you abide by all the rules and regulations, it is difficult to avoid bacteria completely as they are often buried far below the surface of the skin.” Beauty with consequence Researchers estimate that between 1:100 and 1:1000 — depending on the type of filler -develops an unfortunate bacterial infection which, in the worst-case scenario, may leave the person in question with a permanently disfigured face. “Most people are unlikely to have any problems undergoing a filler treatment to smooth their skin. However, it’s a bit like driving a car: there’s nothing wrong with not wearing your seatbelt as long as you don’t hit anything. If you do have an accident, however, it’s almost impossible to walk away unharmed,” says Thomas Bjarnsholt.

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Analysis of the Packaged Wastewater Treatment Market in India

The market is highly fragmented so tie-ups with local market participants could be a game changer. 3. Educational promotions on low operating cost of such systems over the long run is an efficient marketing strategy. 4. Patented cutting-edge technologies enhance the profit share as consumers are not as cost-sensitive as quality sensitive. 5. State governments are promoting such small systems by offering tax breaks, etc., which is leading to many start-ups in this industry. Market OverviewDefinitions Medium Term: 2014-2016 Long Term: 2016-2017 The market covered by this project comprises packaged wastewater treatment plants in India having a capacity of up to X Kilo liters per day (KLD). The scope of this project includes all sorts of wastewater treatment installations within KLD. It doesn’t include parallel pre-treatment facilities. This study covers the break-up of packaged wastewater treatment systems according to end users and also discusses the potential states and sectors for such systems. Revenue is specified in Indian Rupees (INR) Million. Key Questions This Study Will Answer Is the market growing? How long will it continue to grow and at what rate? Which industries are expected to witness major growth for packaged wastewater treatment systems? Will these companies/products/services continue to exist or will they get acquired by other companies?

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New health site lets the crowd rate treatment effectiveness

CureCrowd ratings of treatments for back pain

Nor is there a way to determine whether the information the sites provide is accurate and up to date. The US Department of Health and Human Services’ National Institute on Aging provides guidelines for assessing the trustworthiness of online health information . Among the suggestions are to look for the site’s sponsor and a way to contact the sponsor. Articles should be attributed to a specific author whose qualifications are listed, and all the site’s content should be reviewed by an editorial board or other advisory body. Related stories The US Federal Trade Commission offers a guide to reliable medical information geared specifically to seniors. Among the organizations the site links to are , the Centers for Disease Control and Prevention , and . The US Department of Health and Human Service’s site is one of several government agencies providing safe, reliable health information. (Credit: Screenshot by Dennis O’Reilly/CNET) The claims of alternative-medicine purveyors can be particularly difficult to vet. The National Institutes of Health’s National Center for Complementary and Alternative medicine provides guidelines and resources for evaluating nontraditional health treatments . As with any treatment suggested online, the agency recommends that you check with your health care provider before trying it. Help for your aching back After visiting more than a dozen online resources for back-pain sufferers, the one I found most effective is from InsiderMedicine , not only because it combines video and text explanations of the causes and treatments of back pain, but also because it starts by helping you determine whether your pain is an indication of a medical emergency. In the video, Alan Platt, a physician’s assistant and instructor at the Emory School of Medicine, describes the symptoms that might indicate the need to seek immediate medical help, such as severe pain radiating from your stomach to your back, or loss of bladder control. Another helpful resource in determining whether your back pain requires the attention of a medical professional is Handout on Health: Back Pain from the National Institute of Arthritis and Musculoskeletal and Skin Diseases. The handout recommends that you call your doctor if the pain is due to a recent fall or is accompanied by fever or numbness/weakness in your legs.

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Colon Cancer Prevention Efforts Expanding In Sc

Too Much Sitting Tied to Higher Risk of Colon Polyps in Men

Symptom Checker: Your Guide to Symptoms & Signs: Pinpoint Your Pain

The network estimates it will be able to provide free colonoscopies for 800 people this year, compared with 550 in the 2008-2013 period. The effort has expanded from two counties to 28. Most patients are referred from free clinics or federally qualified health centers to gastroenterologists who have volunteered to perform a certain number of the free exams each year. (Their practices are paid the Medicaid rate for the procedure, but the physicians waive their separate fee.) Despite the procedures being free, many candidates still balked at the opportunity. When you give away something, its not appreciated, Seabrook said. Thats why navigators such as Caldwell are important. She not only explained the procedures importance to Hemingway, she also sat down with him and watched a video on the subject. She thoroughly detailed the preparation process. She reminded him what needed to be done each step along the way. If we get them in the front door, they get it, Caldwell said. We try to make it a personal experience, not just wham, bam, youre done. Based on general population statistics, the 800 exams this year will save two or three lives and about $500,000 in medical costs, Berger said. And those savings will be multiplied if more patients follow the lead of Hemingway.

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Sign Up for MedicineNet Newsletters! MONDAY, Oct. 28 (HealthDay News) — Men who are more sedentary face a higher risk of recurring colon polyps , according to a new study, even if these men break up their downtime with bouts of recreational activities such as walking , jogging or golf. This suggests that extended inactivity is itself a risk factor for noncancerous colon polyps, benign tumors that can give rise to colorectal cancer , the researchers said. Known as “colorectal adenomas,” these polyps typically can be removed after being identified during a colorectal cancer screening, such as a colonoscopy . The recurrence of such polyps, however, seems to be greater among men (but not women) who are relatively less active. The researchers looked at activity levels among more than 1,700 men and women, and found that the more leisurely the men’s lifestyle, the greater their risk for precancerous polyps. Men who spent 11 or more hours a day in seated endeavors — such as writing or reading — were 45 percent more likely to develop polyps than those who spent less than seven hours a day engaged in sedentary behavior. The study, funded by the U.S. National Institutes of Health and the U.S. National Cancer Institute, was schedule for presentation this week at the annual cancer-prevention conference of the American Association for Cancer Research, held in Oxon Hill, Md. “Sedentary behavior is emerging as a risk factor for poor health,” study author Christine Sardo Molmenti, a postdoctoral research fellow in the department of epidemiology at the Columbia University Mailman School of Public Health, said in a conference news release. “Even among those who fulfill daily recommendations for physical activity, lengthy periods of sedentary behavior have been associated with early morbidity and mortality, leading to the ‘active couch potato’ paradigm,” Sardo Molmenti said. Because this study is being presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal. Although the study found an association between sedentary behavior and increased risk of colon polyps in men, it did not prove a cause-and-effect relationship.

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March Is Colorectal Cancer Awareness Month

Saundra Sweeney survived colon cancer. She has no family history of the disease and had no obvious symptoms, so the diagnosis was quite a shock. “I had anemia at age 45 at an annual checkup. And again, at age 50, anemia came up again. They (doctors) wanted to put me on an iron pill. I asked, “What causes anemia?” Doctors told Sweeney it could be one of two things: fatigue or blood in her stool. For this mother of two teenagers, who also worked fulltime, fatigue was a normal part of life. She decided to have some tests done. After blood was found in her stool, Sweeney had a colonoscopy and later a CT scan. The results revealed she had stage four colon cancer. From 2010 until 2012, she underwent treatment at University of Colorado Hospital. Today, she is stable, but goes back for more testing later this month. Sweeney says her story highlights just how important it is to get screened. “Colon cancer is the most preventable, treatable and curable disease, if people would just get their screening. Really, having a colonoscopy is not that big of a deal, ” said Sweeney. March is Colorectal Cancer Awareness month to focus on a cancer that is the number two cancer killer in the United States for cancers that affect both men and women.

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Early detection crucial in colorectal cancer, doctors say

Jared Frattini, a colon and rectal surgeon at Medical Center of Trinity emphasizes early detection is vital to controlling colorectal cancer.

Colorectal cancer is the second leading cause of cancer-related deaths in the United States for both men and women combined. This year, approximately 140,000 new cases of colorectal cancer will be diagnosed and 56,000 people will die from the disease. Big changes in treatment have taken place the last 10 years, Dandamudi explained. A multidisciplinary approach can utilize options including gastroenterology, radiology and surgery, Dandamudi added A tumor board meets weekly to discuss cases, Frattini noted. Blood in the stool or abdominal pain usually are sure clues to pursue treatment. Even those patients who have advanced to the incurable stage four can now expect to live longer, thanks to advancements, Dandamudi said. Surgery techniques for colorectal cancer have changed to include laparoscopic or robotic methods, Frattini noted. Hospitals stays have shortened to about two to three days, he said, instead of five to seven days in the past. Incisions are about half as long in surgeries now. Its not just a hemorrhoid, Frattini said about some patients who indulged in some wishful thinking about early signs of colon cancer. Delays could result in multiple treatments instead of a single option, Dandamudi emphasized about patients who ignore symptoms. While most should seek diagnosis by age 50, those with a family history of colon cancer should consult doctors by age 40, Dandamudi recommended. While the prevalence of colorectal cancer has decreased for patients ages 50 and older, the disease is increasing among the 20-49 age group, Frattini noted.

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Colon cancer: A preventable illness

Yamamoto says. Polyps are removed quick and painlessly like this during the colonoscopy. Dr. Yamamoto has been practicing for 33 years and says he’s watched as technology has completely changed the procedure, making it safer and less invasive. “It’s much more superior than what we did thirty years ago,” Dr. Yamamoto says. When Dr. Yamamoto started a colonoscopy procedures back in the late 1978 he says it would take about two and half hours to complete the procedure. Pavia’s colonoscopy took 20 minutes. “It’s better to know what’s going on,” Pavia says. Dr.

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1 In 5 Colon Cancer Cases Are Young Adults

In most patients, by the time the condition is properly diagnosed, about 50 to 60 per cent already have advanced stage cancer (stage 3 or 4). Screening methods for colorectal cancer Faecal immunological stool test (FIT) or faecal occult blood test (FOBT), which can be done in the privacy and comfort of ones home, helps detect blood in stool that cannot be seen by the naked eye. The user simply collects stool samples for two consecutive days using a simple test kit and sends it back to a lab for processing. If the results are positive above a certain predetermined level, a colonoscopy is then needed to properly rule out colon cancer. However, when taking the FIT, care must be taken not to consume certain medications prior to the test as they may interfere with the results. Related article: TCM for cancer treatment, is it as safe as it claims to be? Colonoscopy In a colonoscopy, after prior bowel cleansing, a fibre-optic flexible tube is inserted up the rectum. Although generally not painful, this test can be uncomfortable; hence a mild sedative is usually given to relieve any discomfort. As these sedatives have a mild amnesic effect, a patient may even forget the specific details of the procedure. As a colonoscopy detects both pre-cancerous lesions (such as polyps) as well as cancerous ones, it remains the gold standard for colorectal cancer screening. Polyps can be immediately removed during the colonoscopy. Early detection is your best protection against colorectal cancer Citing the survival rates for different stages of colon cancer, Associate Professor Tang explains, In stage 1 of the disease, the cure rate is greater than 90 per cent. In the later stages 3 and 4, the average five-year survival rates are 40-60 per cent and 10 per cent respectively. Hence, early detection is of paramount importance. Always remember, when it comes to colorectal cancer: If youre above 50, insist on going for a screening every three years whether you have symptoms or not.

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Colorectal Cancer Increasing in Young Adults

The increase was 33 percent for men, but not statistically significant for women. There was no increase for African-Americans, but unfortunately, this group of 20 to 49-year-old men and women has a higher risk. Their numbers are 12.7 and 10.8 cases per 100,000. Reasons for the Increase Among Young Adults Researchers believe the reasons for the increase in colorectal cancer in the younger generation are from changes in the American lifestyle. Diets that consist of a high intake of red and processed meat and diets that are low in milk and calcium have been liked as the possible cause. As a nation, many of the young eat hamburgers and sodas at fast-food places. The result is not only a rise in cancer, but also a rise in obesity and low physical activity. The American Cancer Society recommends that people eat plenty of fruits, vegetables, and whole grains. Exercise should be done for at least 30 minutes for five days a week. This will help protect against cancer, but in not a 100 percent protection against a person having colorectal cancer. Screening Usually Not Considered When Patient is Below Age 50 For most people under the age of 50, screening for colorectal cancer is generally not done. Doctors do the screening only when the patient has a family history, chronic inflammatory bowel disease or a predisposing genetic condition. Since they don’t screen most patients below 50, this gives the benign polyps time to turn into invasive cancer.


Key Link Responsible For Colon Cancer Initiation, Metastasis

For instance, more than 20 percent of patients with a form of inflammatory bowel disease (IBD) develop colorectal cancer within 30 years of diagnosis. This colitis-associated cancer has a slow progression, but a very poor response to treatment and a high mortality rate. Researchers have known that the broad mechanisms of cancer involve an interplay with the immune system response that includes: recruiting immune cells that influence the tumor microenvironment, escaping from host immunosurveillance and suppression, shifting of the host immune response, and tumor-associated angiogenesis to establish the blood supply. For the study, the research team first “knocked-out” or removed the CXCR2 gene in mice, and found that the signs typically associated with inflammation were prevented. Furthermore, they demonstrated that CXCR2 dramatically suppressed colonic inflammation and the colitis associated tumor formation, growth and progression in mice. CXCR2 decorates the outer part of immune cells called myeloid-derived suppressor cells, or MDSCs, that work to block the immune response of killer CD8+ T cells. In the knockout mice, without CXCR2 present, the MDSC cells could no longer migrate from the circulatory system to the colon, dodge the killer CD8+ T cell immune response, and feed the blood supply of the tumor environment. Furthermore, when they transplanted normal MDSC cells (with normal CXCR2) into the knockout mice, tumor formation was restored. “These results provide the first genetic evidence that CXCR2 is required for recruitment of MDSCs into inflamed colonic mucosa and colitis-associated tumors,” said DuBois. For DuBois, who has devoted his career to unraveling the inflammatory circuitry responsible for colon cancer, the results help connect the dots between the immune system, inflammation and tumor formation and metastasis. DuBois’ team was the first to show that colorectal tumors contained high levels of the enzyme cyclo-oxygenase-2 (COX-2), a key step in the production of pro-inflammatory mediators such as prostaglandin E2 (PGE2). PGE2 triggers production of a CXCR2 molecule that fits into CXCR2 like a baseball into a glove’s pocket and activates it. CXCR2, like the pied piper, recruits MDSCs from the bloodstream to sites of inflammation, causing the colon cancer tumors to evade the immune killer CD8+ T immune response. “Our findings reveal not only how MDSCs are recruited to local inflamed tissues and tumor microenvironment and how local MDSCs contribute to colorectal cancer progression, but now also provide a rationale for developing new therapeutic approaches to subvert chronic inflammation- and tumor-induced immunosuppression by using CXCR2 antagonists and neutralizing antibodies,” said DuBois. Story Source: The above story is based on materials provided by Arizona State University . Note: Materials may be edited for content and length.

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Treating Unresectable Metastatic Colorectal Cancer

A systematic review showed that approximately 50% of salvage patients have an overall survival of more than 12 months after this nuclear medicine therapy. Colorectal cancer is the third most commonly diagnosed type of cancer worldwide in men and the second in women, and it is also the third most common cause of death. In approximately 50% of patients, metastases to the liver are present at diagnosis or during follow-up, which account for a large portion of morbidity and mortality in patients. A structured review was performed by researchers to gather all available evidence on radioembolization for the specific group of patients with colorectal cancer liver metastases. “Although quite some reviews are printed on the subject of radioembolization, we felt that a structured and comprehensive review on survival and response data for these patients was lacking,” said lead author Charlotte E.N.M. Rosenbaum, PhD, of University Medical Center Urecht in The Netherlands. The study was published in the November issue of The Journal of Nuclear Medicine (2013; doi:10.2967/jnumed.113.119545). The research team reviewed a total of 13 articles on Y-90 radioembolization as a monotherapy and 13 articles on Y-90 radioembolization as a combined with chemotherapy. Among the studies, disease control rates (ie, complete response, partial response, and stable disease) ranged from 29% to 90% in the monotherapy studies, which involved 901 patients. In the studies in which Y-90 radioembolization was combined with chemotherapy, involving 472 patients, disease control rates ranged from 59% to 100%. “From the studies included in this systematic review, survival proportions of approximately 50% were found. Therefore, in this group of salvage colorectal cancer liver metastases patients who otherwise have no regular treatment options and a life expectancy of less than 6 months, Y-90 radioembolization seems to be a hopeful treatment option,” noted Rosenbaum. “Our paper shows all published data on this subject from the first randomized trial onwards. Furthermore, we have determined 12-month survival proportions for all included articles to provide a better overview and to better allow for comparisons. Finally, this overview of the literature shows which topics have not been the focus of much research and may thus be interesting for further work.” Similar Articles

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Nuclear medicine improves survival from colorectal cancer metastasis to the liver

Looking more closely at location, moderator John L. Marshall, MD, poises the question of selecting treatment for patients with KRAS G13D mutations. Johanna Bendell, MD, explains that recent findings contradict the initial pooled analysis of the CRYSTAL and OPUS trials, which showed that cetuximab was beneficial in patients with KRAS G13D mutations. As a result, she believes the role of the G13D is unclear and patients who test positive should be enrolled in clinical trials. The role of BRAF mutations in CRC has evolved, as more data becomes available. Axel Grothey, MD, explains that approximately 8% of patients with metastatic CRC have a BRAF mutation. Unfortunately, Grothey notes, BRAF mutations denote a poorer prognosis and a standard therapy currently does not exist. The treatment of BRAF mutant metastatic CRC is evolving, Lenz states. Moreover, he notes, these tumors seem to respond to immunotherapies. The need for effective treatment approaches in this space enhances the importance of molecular testing and enrollment in clinical trials. At this point, Bendell notes, research is just beginning to scratch the surface of what is possible in the treatment of CRC. The panel remains optimistic that a target will be found that shows dramatic responses, similar to those seen in lung cancer with ALK and EGFR and in breast cancer with HER2. View More From This Discussion Episode 1 Managing Adjuvant Treatment in Colorectal Cancer, Part I Dr.

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Bowel Cancer: Prevention And How To Spot The Symptoms

Colorectal Cancer

Its the fourth most common cancer in the UK, after breast , lung and prostate cancer . Around 41,600 people are diagnosed with bowel cancer each year, with a slightly higher rate in men . Most bowel cancers affect people aged 65 or older, but as charity Beating Bowel Cancer reveals , the cancer is a slow grower – it can develop over a period of up to 10 years, and then begins to spread and affect other areas of your body. Most bowel cancers are in the large bowel,” says Dr Zollinger-Read, “and about 1 in 3 in the back passage. Its most common in older people – more than eight out of 10 bowel cancers are diagnosed in people aged 60 or over. In many cases, its hard to know the exact cause but there are some things that put you more at risk. If you have a strong family history of bowel cancer, youre more at risk of developing the disease. About one in 20 bowel cancers are caused by inherited conditions If someone in your family, and especially if a few people on the same side, have been diagnosed with bowel cancer, speak to your GP. They may refer you to a specialist genetics service.” Story continues below the slideshow: Loading Slideshow Eat Fiber From Whole Grains Researchers from Britain and the Netherlands found that the more total dietary fiber and cereal fiber people consumed, the lower their colorectal cancer risk. For example, people who consumed an extra 90 grams of whole grains a day also had a 20 percent lower risk of colorectal cancer, according to the British Medical Journal review. However, that same study didn’t show a link between eating fiber from fruits and vegetables and a lowered colorectal cancer risk, meaning there may be something else in whole grains at work, too. Take Aspirin Researchers from the Leiden University Medical Center in the Netherlands found that people who take aspirin once a day have a 30 percent decreased risk of dying from colorectal cancer, if taken for at least a nine-month period. And, the benefit extended to after a person had been diagnosed with colorectal cancer. The researchers found that people who had already been diagnosed and who took aspirin had a 23 percent decreased risk of dying from the disease, compared with people who didn’t take it at all. Eat Chocolate (Maybe) The Daily Mail reported on a study in mice, published in the journal Molecular Nutrition and Food Research, showing that rats exposed to a carcinogen developed fewer colon cancer lesions than rats if they consumed high-cocoa diets. “Being exposed to different poisons in the diet like toxins, mutagens and procarcinogens, the intestinal mucus is very susceptible to pathologies,” study researcher Maria Angeles Martin Arribas, a researcher at the Institute of Food Science and Technology and Nutrition, said in a statement.

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The large intestine carries the remnants of digested food from the small intestine and eliminates them as waste through the anus. Colorectal tumors begin as polyps (small growths) on the inside of the large intestine. Polyps that aren’t removed eventually can become cancerous, penetrate through the wall of the colon or rectum, and spread to other areas. Colorectal cancer is a common type of cancer in the United States. It is the second most common cause of death from cancer in the country. The American Cancer Society estimates that 145,000 new cases of colorectal cancer will have been diagnosed in 2005, and about 56,000 people in the United States will have died of this disease. Risk Factors The older you get, the more likely you are to develop colorectal cancer. Other factors that increase the risk of developing colorectal cancer include: Family history – Heredity may play a role in up to 10% of all cases of colorectal cancer. Genetic defects have been linked to a number of cancer syndromes that run in families and make family members more likely to develop polyps and colorectal cancer. A personal history of the disease – If you have been diagnosed with colorectal cancer once, you have an increased risk of developing the disease again. A personal history of adenomatous polyps – A personal history of polyps also increases the risk. Inflammatory bowel disease (chronic ulcerative colitis, Crohn’s disease) – The longer and more severely the colon is inflamed, the greater the risk of cancer.

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